That means no mouse or keyboard. Both work on other computers. I have tried other USB devices... Nothing. All 10 are out. This is what happened... I was on the computer. A cat was sleeping on a box near it. (I know, cats and computers do not mix. Cats have been banned from my man room). This clumsy fat cat fell off the box and hit the front of my comp. There are no buttons on the front except for the dvd button. It was not a huge hit. She just rolled off on to it. I opened the case up and all of the power lines seem well connected. I fiddled with it and got the mouse to light up. Still does not work. The keyboard has yet to light up. What would take out all 10 USB connections? The comp boots up fine. It connects just fine. I know this by watching my virus protection load up. I am out of my league here. One more question. Should the offending cat be a wall ornement or a furry mouse pad?